Yes, splice is a Scrabble word!
...and is worth 10 points in Scrabble, and 13 points in Words with Friends
splice
Verb
1. Join the ends of
2. Perform a marriage ceremony
3. Join together so as to form new genetic combinations
4. Join by interweaving strands
Noun
1. A junction where two things (as paper or film or magnetic tape) have been joined together
2. Joint made by overlapping two ends and joining them together
What Scrabble words can I make with the letters in splice?
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words