Yes, sign is a Scrabble word!
...and is worth 5 points in Scrabble, and 7 points in Words with Friends
sign
Verb
1. Mark with one's signature; write one's name (on)
2. Approve and express assent, responsibility, or obligation
3. Be engaged by a written agreement
4. Engage by written agreement
5. Communicate silently and non-verbally by signals or signs
6. Place signs, as along a road
7. Communicate in sign language
8. Make the sign of the cross over someone in order to call on God for protection; consecrate
Adjective
1. Used of the language of the deaf
Noun
1. A perceptible indication of something not immediately apparent (as a visible clue that something has happened)
2. A public display of a message
3. Any nonverbal action or gesture that encodes a message
4. Structure displaying a board on which advertisements can be posted
5. (astrology) one of 12 equal areas into which the zodiac is divided
6. (medicine) any objective evidence of the presence of a disorder or disease
7. Having an indicated pole (as the distinction between positive and negative electric charges)
8. An event that is experienced as indicating important things to come
9. A gesture that is part of a sign language
10. A fundamental linguistic unit linking a signifier to that which is signified
11. A character indicating a relation between quantities
What Scrabble words can I make with the letters in sign?
4 Letter Words
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3 Letter Words
2 Letter Words