Yes, domain is a Scrabble word!
...and is worth 9 points in Scrabble, and 11 points in Words with Friends
domain
Noun
1. A particular environment or walk of life
2. Territory over which rule or control is exercised
3. (mathematics) the set of values of the independent variable for which a function is defined
4. People in general; especially a distinctive group of people with some shared interest
5. The content of a particular field of knowledge
What Scrabble words can I make with the letters in domain?
6 Letter Words
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3 Letter Words
2 Letter Words