Yes, sister is a Scrabble word!
...and is worth 6 points in Scrabble, and 6 points in Words with Friends
sister
Noun
1. A female person who has the same parents as another person
2. (Roman Catholic Church) a title given to a nun (and used as a form of address)
3. A female person who is a fellow member of a sorority or labor union or other group
4. (slang) sometimes used as a term of address for attractive young women
What Scrabble words can I make with the letters in sister?
6 Letter Words
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words