Yes, SETONS is a Scrabble word!

Letter values in Scrabble US: S 1, E 1, T 1, O 1, N 1, S 1.

Is it a valid word?

SETONS is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

United States religious leader who was the first person born in the United States to be canonized (1774-1821)

Also: elizabeth seton, saint elizabeth ann bayley seton, mother seton.