Yes, PROFOUND is a Scrabble word!

Letter values in Scrabble US: P 3, R 1, O 1, F 4, O 1, U 1, N 1, D 2.

Is it a valid word?

PROFOUND is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

showing intellectual penetration or emotional depth
of the greatest intensity; complete
far-reaching and thoroughgoing in effect especially on the nature of something
coming from deep within one
(of sleep) deep and complete
situated at or extending to great depth; too deep to have been sounded or plumbed

Not playable in Scrabble US: UNFATHOMED.