Yes, EXPLODE is a Scrabble word!

Letter values in Scrabble US: E 1, X 8, P 3, L 1, O 1, D 2, E 1.

Is it a valid word?

EXPLODE is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

cause to burst with a violent release of energy
burst outward, usually with noise
show a violent emotional reaction
be unleashed; emerge with violence or noise
destroy by exploding
cause to burst as a result of air pressure; of stop consonants like /p/, /t/, and /k/
drive from the stage by noisy disapproval
show (a theory or claim) to be baseless, or refute and make obsolete
burst and release energy as through a violent chemical or physical reaction
increase rapidly and in an uncontrolled manner

Also: blow up, set off, burst forth, break loose.