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Yes, misuse is a Scrabble word!
...and is worth 8 points in Scrabble, and 10 points in Words with Friends
1. Apply to a wrong thing or person; apply badly or incorrectly
2. Change the inherent purpose or function of something
1. Improper or excessive use
What Scrabble words can I make with the letters in misuse?
5 Letter Words
4 Letter Words
3 Letter Words
2 Letter Words