Yes, muckle is a Scrabble word!
...and is worth 14 points in Scrabble, and 18 points in Words with Friends
muckle
Noun
1. (often followed by `of') a large number or amount or extent
What Scrabble words can I make with the letters in muckle?
4 Letter Words
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Words that can be created with an extra letter added to muckle:
S:muckles