Yes, lyssas is a Scrabble word!

...and is worth 9 points in Scrabble, and 9 points in Words with Friends

lyssas

Noun

1. An acute viral disease of the nervous system of warm-blooded animals (usually transmitted by the bite of a rabid animal); rabies is fatal if the virus reaches the brain

What Scrabble words can I make with the letters in lyssas?

5 Letter Words

lyssa
sassy
slays

4 Letter Words

lass
lays
sals
sass
says
slay

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Words that can be created with an extra letter added to lyssas:

I:sassily