Yes, PUEBLO is a Scrabble word!

Letter values in Scrabble US: P 3, U 1, E 1, B 3, L 1, O 1.

Is it a valid word?

PUEBLO is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

a member of any of about two dozen Native American peoples called `Pueblos' by the Spanish because they live in pueblos (villages built of adobe and rock)
a city in Colorado to the south of Colorado Springs
a communal village built by Indians in the southwestern United States