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Yes, serene is a Scrabble word!
...and is worth 6 points in Scrabble, and 7 points in Words with Friends
1. Not agitated; without losing self-possession
2. Completely clear and fine
What Scrabble words can I make with the letters in serene?
6 Letter Words
5 Letter Words
4 Letter Words
3 Letter Words
2 Letter Words