Yes, PYXIDES is a Scrabble word!

Letter values in Scrabble US: P 3, Y 4, X 8, I 1, D 2, E 1, S 1.

Is it a valid word?

PYXIDES is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

fruit of such plants as the plantain; a capsule whose upper part falls off when the seeds are released
a constellation in the southern hemisphere near Puppis and Antlia
a small box used by ancient Greeks to hold medicines