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Yes, mutes is a Scrabble word!
...and is worth 7 points in Scrabble, and 9 points in Words with Friends
1. Deaden (a sound or noise), especially by wrapping
1. A deaf person who is unable to speak
2. A device used to soften the tone of a musical instrument
What Scrabble words can I make with the letters in mutes?
4 Letter Words
3 Letter Words
2 Letter Words