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Yes, knob is a Scrabble word!
...and is worth 10 points in Scrabble, and 12 points in Words with Friends
1. A circular rounded projection or protuberance
2. A round handle
3. Any thickened enlargement
4. An ornament in the shape of a ball on the hilt of a sword or dagger
What Scrabble words can I make with the letters in knob?
4 Letter Words
3 Letter Words
2 Letter Words