Yes, GHETTOS is a Scrabble word!

Letter values in Scrabble US: G 2, H 4, E 1, T 1, T 1, O 1, S 1.

Is it a valid word?

GHETTOS is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

formerly the restricted quarter of many European cities in which Jews were required to live
any segregated mode of living or working that results from bias or stereotyping
a poor densely populated city district occupied by a minority ethnic group linked together by economic hardship and social restrictions