Yes, TWEEDS is a Scrabble word!

Letter values in Scrabble US: T 1, W 4, E 1, E 1, D 2, S 1.

Is it a valid word?

TWEEDS is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

thick woolen fabric used for clothing; originated in Scotland
(usually in the plural) trousers made of flannel or gabardine or tweed or white cloth