Yes, PIXIES is a Scrabble word!

Letter values in Scrabble US: P 3, I 1, X 8, I 1, E 1, S 1.

Is it a valid word?

PIXIES is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

(folklore) fairies that are somewhat mischievous
creeping evergreen shrub having narrow overlapping leaves and early white star-shaped flowers; of the pine barrens of New Jersey and the Carolinas
creeping evergreen shrub having narrow overlapping leaves and early white star-shaped flowers; of the pine barrens of New Jersey and the Carolinas
(folklore) fairies that are somewhat mischievous

Also: pyxidanthera barbulata.