Yes, xis is a Scrabble word!
...and is worth 10 points in Scrabble, and 10 points in Words with Friends
xis
Noun
1. The cardinal number that is the sum of ten and one
2. The 14th letter of the Greek alphabet
What Scrabble words can I make with the letters in xis?
3 Letter Words
2 Letter Words
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1 Anagram of Xis
Words that can be created with an extra letter added to xis:
A:axis