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Yes, mules is a Scrabble word!
...and is worth 7 points in Scrabble, and 10 points in Words with Friends
1. Hybrid offspring of a male donkey and a female horse; usually sterile
2. A slipper that has no fitting around the heel
What Scrabble words can I make with the letters in mules?
4 Letter Words
3 Letter Words
2 Letter Words