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Yes, lisle is a Scrabble word!
...and is worth 5 points in Scrabble, and 7 points in Words with Friends
1. A fabric woven with lisle thread
2. A strong tightly twisted cotton thread (usually made of long-staple cotton)
What Scrabble words can I make with the letters in lisle?
4 Letter Words
3 Letter Words
2 Letter Words