Yes, gesso is a Scrabble word!
...and is worth 6 points in Scrabble, and 7 points in Words with Friends
gesso
Noun
1. Gypsum or plaster of Paris spread on a surface to make it suitable for painting or gilding (or a surface so prepared)
What Scrabble words can I make with the letters in gesso?
5 Letter Words
4 Letter Words
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3 Letter Words
2 Letter Words