Yes, ENCYCLOPEDIA is a Scrabble word!

Letter values in Scrabble US: E 1, N 1, C 3, Y 4, C 3, L 1, O 1, P 3, E 1, D 2, I 1, A 1.

Is it a valid word?

ENCYCLOPEDIA is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

a reference work (often in several volumes) containing articles on various topics (often arranged in alphabetical order) dealing with the entire range of human knowledge or with some particular specialty