Yes, BEEFALO is a Scrabble word!

Letter values in Scrabble US: B 3, E 1, E 1, F 4, A 1, L 1, O 1.

Is it a valid word?

BEEFALO is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

hardy breed of cattle resulting from crossing domestic cattle with the American buffalo; yields leaner beef than conventional breeds