Yes, VARIOLA is a Scrabble word!

Letter values in Scrabble US: V 4, A 1, R 1, I 1, O 1, L 1, A 1.

Is it a valid word?

VARIOLA is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

a highly contagious viral disease characterized by fever and weakness and skin eruption with pustules that form scabs that slough off leaving scars

Also: variola major.