Yes, SOPHISTICATIONS is a Scrabble word!

Letter values in Scrabble US: S 1, O 1, P 3, H 4, I 1, S 1, T 1, I 1, C 3, A 1, T 1, I 1, O 1, N 1, S 1.

Is it a valid word?

SOPHISTICATIONS is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

uplifting enlightenment
a deliberately invalid argument displaying ingenuity in reasoning in the hope of deceiving someone
being expert or having knowledge of some technical subject
the quality or character of being intellectually sophisticated and worldly through cultivation or experience or disillusionment
falsification by the use of sophistry; misleading by means of specious fallacies