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Yes, reply is a Scrabble word!
...and is worth 10 points in Scrabble, and 11 points in Words with Friends
1. React verbally
1. A statement (either spoken or written) that is made to reply to a question or request or criticism or accusation
2. The speech act of continuing a conversational exchange
What Scrabble words can I make with the letters in reply?
5 Letter Words
4 Letter Words
3 Letter Words
2 Letter Words