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Yes, puke is a Scrabble word!
...and is worth 10 points in Scrabble, and 12 points in Words with Friends
1. Eject the contents of the stomach through the mouth
1. A person who is deemed to be despicable or contemptible
2. The matter ejected in vomiting
What Scrabble words can I make with the letters in puke?
3 Letter Words
2 Letter Words