Yes, OFFICE is a Scrabble word!

Letter values in Scrabble US: O 1, F 4, F 4, I 1, C 3, E 1.

Is it a valid word?

OFFICE is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

place of business where professional or clerical duties are performed
an administrative unit of government
the actions and activities assigned to or required or expected of a person or group
(of a government or government official) holding an office means being in power
professional or clerical workers in an office
a religious rite or service prescribed by ecclesiastical authorities
a job in an organization

Also: business office, federal agency, government agency, office staff.