Yes, guys is a Scrabble word!
...and is worth 8 points in Scrabble, and 9 points in Words with Friends
guys
Verb
1. Subject to laughter or ridicule
2. Steady or support with a guy wire or cable
Noun
1. An informal term for a youth or man
2. An effigy of Guy Fawkes that is burned on a bonfire on Guy Fawkes Day
3. A cable, wire, or rope that is used to brace something (especially a tent)
What Scrabble words can I make with the letters in guys?
3 Letter Words
2 Letter Words