Yes, AUTOPILOT is a Scrabble word!

Letter values in Scrabble US: A 1, U 1, T 1, O 1, P 3, I 1, L 1, O 1, T 1.

Is it a valid word?

AUTOPILOT is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

a cognitive state in which you act without self-awareness
a navigational device that automatically keeps ships or planes or spacecraft on a steady course

Also: automatic pilot, robot pilot.