Yes, PROFESSION is a Scrabble word!

Letter values in Scrabble US: P 3, R 1, O 1, F 4, E 1, S 1, S 1, I 1, O 1, N 1.

Is it a valid word?

PROFESSION is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

the body of people in a learned occupation
an occupation requiring special education (especially in the liberal arts or sciences)
an open avowal (true or false) of some belief or opinion
affirmation of acceptance of some religion or faith