Yes, INSTRUMENTATION is a Scrabble word!

Letter values in Scrabble US: I 1, N 1, S 1, T 1, R 1, U 1, M 3, E 1, N 1, T 1, A 1, T 1, I 1, O 1, N 1.

Is it a valid word?

INSTRUMENTATION is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

an artifact (or system of artifacts) that is instrumental in accomplishing some end
the act of providing or using the instruments needed for some implementation
the instruments called for in a musical score or arrangement for a band or orchestra
the act of arranging a piece of music for an orchestra and assigning parts to the different musical instruments