Yes, fluke is a Scrabble word!
...and is worth 12 points in Scrabble, and 14 points in Words with Friends
fluke
Noun
1. A stroke of luck
2. A barb on a harpoon or arrow
3. Flat bladelike projection on the arm of an anchor
4. Either of the two lobes of the tail of a cetacean
5. Parasitic flatworms having external suckers for attaching to a host
What Scrabble words can I make with the letters in fluke?
4 Letter Words
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2 Letter Words