Yes, DEGENERATION is a Scrabble word!

Letter values in Scrabble US: D 2, E 1, G 2, E 1, N 1, E 1, R 1, A 1, T 1, I 1, O 1, N 1.

Is it a valid word?

DEGENERATION is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

the process of declining from a higher to a lower level of effective power or vitality or essential quality
the state of being degenerate in mental or moral qualities
passing from a more complex to a simpler biological form