Yes, COMPREHEND is a Scrabble word!

Letter values in Scrabble US: C 3, O 1, M 3, P 3, R 1, E 1, H 4, E 1, N 1, D 2.

Is it a valid word?

COMPREHEND is a valid word in the official Scrabble dictionary (US), the UK Scrabble Dictionary and Words with Friends (ENABLE).

get the meaning of something
to become aware of through the senses
include in scope; include as part of something broader; have as one's sphere or territory

Also: get the picture.